Baltimore officials say 30 people were shot overnight at a block party near the South Baltimore neighborhood of Brooklyn Homes.
Police say three people are in critical condition and two people have died.
Police say they received multiple calls about the shooting.
Baltimore Mayor Brandon Scott told CNN that the shooting highlights “the need to deal with access” to guns not only in Baltimore, but across the country.
Acting Baltimore Police Commissioner Richard Worley described the crime scene as “extensive.” He said 20 of the victims were able to walk to the hospital.
Mayor Scott addressed the assailants, “I want those who are responsible to hear me and hear me very clearly. We will not stop until we find you, and we will find you. Until then, I hope with every single breath that you take that you think about the lives that you took and you think about the lives that you impacted here tonight."