Israelis have observed a moment of silence in memory of the 6 million Jews who died in the Holocaust.
Sirens wailed across Israel and traffic came to a halt Monday as the country marked its Holocaust Remembrance Day.
Flags flew at half-staff, and radio and television stations dedicated their broadcasts to remembering the Holocaust.
More than 200,000 Holocaust survivors currently live in Israel.
On the eve of the event, Israeli Prime Minister Benjamin Netanyahu said the world must denounce Iran and others calling for the destruction of Israel.
Netanyahu told a large crowd at Yad Vashem Holocaust museum in Jerusalem on Sunday that Israel must not ignore threats to its existence. He accused Iran of arming itself with nuclear weapons to try to destroy Israel.
The U.N. Security Council has issued four sets of sanctions against Iran for its refusal to stop enriching uranium, a process that can be used to make nuclear weapons. Iran says its atomic program is peaceful.
Some information for this report was provided by AP.